Alpha-Tocopherol Serum Levels Are Increased in Caucasian Women with Uterine Fibroids: A Pilot Study
Table 2
Association between studied risk factors and uterine fibroids occurrence.
Control group (n=62 )
UF group (n=100)
Crude
Adjusted for age
OR
95% CI
p
OR
95% CI
p
UF in family, n (%)
9 (14.5%)
42 (42%)
4.26
1.88-9.65
<0.001
4.30
1.89-9.76
<0.001
Obesity (BMI ≥30kg/m2), n (%)
4 (6.5%)
21 (21%)
3.85
1.24-11.93
0.018
3.64
1.17-11.36
0.025
Delivery (one or more), n (%)
42 (68%)
51 (51%)
0.50
0.25-0.96
0.037
0.26
0.11-0.61
0.002
α-tocopherol, n (%)
<7.26 μg/ml
29 (48%)
12 (12%)
1.0
1.0
7.26-9.09 μg/ml
18 (29%)
22 (22%)
2.95
1.16-7.49
0.021
2.91
1.11-7.63
0.027
9.10-11.92 μg/ml
10 (16%)
31 (31%)
7.49
2.77-20.27
<0.001
7.25
2.56-20.51
<0.001
>11.92 μg/ml
5 (8%)
35 (35%)
16.92
5.24-54.53
<0.001
18.05
4.81-67.79
<0.001
Crude and age-adjusted logistic regression analysis. Quartiles of α-tocopherol measurements were used in statistical analyses (n: number of subjects included in each group; m: meters; kg: kilograms; μg: micrograms; ml: milliliters; BMI: body mass index; UF: uterine fibroid; OR: odds ratio; and CI: confidence interval).
