Clinically Symptomatic Pericardial Effusions in Hospitalized Systemic Sclerosis Patients: Demographics and Management

Table 3

Admission demographics, presenting symptoms, workups, and outcomes by subgroup.

	Medical therapy (, 22 admissions)	Procedure (, 10 admissions)
Demographics
Sex	15 F, 3 M	4 F, 1 M
Age	62.1 (7.1)	51.8 (9.2)
Race	12 C, 3 AA, 2 other, and 1 unknown	2 C, 2 AA, and 1 unknown
Limited versus diffuse	6 limited, 1 diffuse, and 11 unknown	5 diffuse
Scleroderma disease characteristics
Raynaud phenomenon	6	2
Digital ulcers	1	0
Interstitial lung disease	5	2
Esophageal involvement	2	0
Symptoms
Shortness of breath	12	3
Chest pain	2	0
Fever	2	0
Workup
Reported hypoxia	7	0
Pericardial effusion size	1 small, 12 mod-large, 5 large	1 mod, 4 large
Right heart failure	11	0
Tamponade physiology	2	2
Pulmonary artery hypertension	14 (2 unknown)	3
PASP by echo (mmHg)	79.8 45	39.7 11
WBC (10^9/L)	10 5.2	8.7 4.8
Hgb (g/dL)	11.6 2.1	10.3 2.8
Plt (10^9/L)	292 126	275 150
Cr (mg/dL)	1.2 0.51	2.6 2.5
BUN (mg/dL)	22.6 7.7	27.5 31
AST (U/L)	17.4 6.5	15.5 2 (2 patients)
ALT (U/L)	25.2 9.1	37.5 12 (2 patients)
proBNP (pg/ml)	4671.6 4011	338.5 269
ANA	10 pos, 2 neg	4 pos, 1 neg
ANA pattern	2 nucleolar, 4 centromeres, 2 speckled, 1 diffuse, and 1 unknown	2 nucleolar, 1 speckled, and 1 diffuse
Scl-70 Ab	12 neg	4 neg
ESR (mm/hr)	51.6 31	None reported
CRP (mg/dL)	47 46	1.9 (1 patient)
Outcomes
Readmission in 90 days	3 readmissions in 2 patients	1
Death (as of 2/2017)	7 (2 during the admission)	1