Review Article

Essential Oils as Repellents against Arthropods

Table 1

An overview of commercially available repellents of synthetic and natural origins.

RepellentActive compoundRepellency Safety/ToxicityOrigin

DEETN,N-diethyl-3-methyl-benzamide. (N, N-diethyl-m-toluamide)
23.8% (6.65%) DEET provides about 5 (2) hours of protection against mosquitoes [92]Potential neuro toxicity if applied under sunscreen.
EPA toxicity category III (slightly toxic)

Picaridin(2-(2-hydroxyethyl)-1- piperidine-carboxylic acid 1-methylpropyl-ester)
Picaridin 20% works as well as DEET 20% [93]Possible skin irritation.
EPA toxicity category III (slightly toxic)

Permethrin(3-phenoxybenzyl (1RS)- cis, trans-3-(2, 2- dichlorovinyl)-2, 2- dimethyl-cyclo-propanecarboxylate)
Permethrin medication is applied to skin as a cream or lotion.
Permethrin repellents should be used on clothes.
Not useful on skin. Possible skin irritation.
(EPA, likely human carcinogen)
Chrysanthemum spp.

PMD
(Oil of lemon eucalyptus)
(p-menthane-3, 8-diol)
PMD is as effective as DEET when used in like quantities.
PMD provides about 2 hours of protection against mosquito bites [94]
Potential skin irritation in atopic individuals.
EPA toxicity category I(highly toxic)
Lemon eucalyptus

Citronella(3, 7-dimethyloct-6-en-1-al)
The complete protection time (CPT) of DEET (360 min) was much longer than the CPTs of citronella (10.5 min) from mosquitoes [95]Potential eye and skin irritation and allergies for Ceylon type
EPA toxicity category IV (practically non-toxic)
Cymbopogon spp.