BioMed Research International / 2018 / Article / Tab 1

Research Article

Association of Androgen Excess with Glucose Intolerance in Women with Polycystic Ovary Syndrome

Table 1

Characteristics of subjects based on different glucose tolerance status.

NGTPrediabetesT2DM

22611933-
Age, 29.0 ± 4.28.5 ± 4.40.001
Oligomenorrhea, %167 (73.9)79 (66.4)25 (75.8)0.259
Hyperandrogenism, %145 (64.2)72 (60.5)21 (63.6)0.834
Polycystic ovaries, %190 (84.1)97 (81.5)29 (87.9)0.717
BMI, kg/m229.3 ± 5.530.6 ± 4.31.5 ± 4.0.012
Waist circumference, cm90.6 ± 14.496.1 ± 12.97.2 ± 8.0.014
Waist-to-hip ratio0.88 ± 0.080.91 ± 0.00.92 ± 0.00.014
Systolic BP, mmHg120.3 ± 13.7125.4 ± 14.134.6 ± 17.<0.001
Diastolic BP, mmHg78.7 ± 11.783.5 ± 12.91.3 ± 13.<0.001
Hypertension, %32 (14.2)32 15 <0.001
Fasting glucose, mmol/L4.9 ± 0.45.4 ± 0.6.4 ± 1.<0.001
Fasting insulin, uIU/mL<0.001
Family history of diabetes, %36 (15.9)33 (27.7)6 (18.2)0.056
Triglycerides, mmol/L1.5 (1.1–2.2)1.7 1.8 (1.4–2.4)0.028
Total cholesterol, mmol/L4.7 ± 0.94.8 ± 1.14.7 ± 0.70.801
HDL-cholesterol, mmol/L1.2 ± 0.31.1 ± 0.51.0 ± 0.20.296
LDL-cholesterol, mmol/L2.7 ± 0.72.7 ± 0.92.8 ± 0.70.659
Testosterone, nmol/L1.0 (0.7–1.5)1.1 (0.7–1.6)1.4 0.033
DHEAS, ug/dL235.9 ± 109.0235.9 ± 104.9216.6 ± 106.40.672
SHBG, nmol/L18.2 (11.2–26.9)0.028
FAI5.0 (2.8–7.6)6.2 7.9 <0.001

NGT, normal glucose tolerance; T2DM, type 2 diabetes mellitus; BMI, body mass index; BP, blood pressure; DHEAS, sulfated dehydroepiandrosterone; SHBG, sex hormone-binding globulin; FAI, free androgen index. Data are presented as mean ± SD, median (25th–75th interquartile range), or (%). versus NGT group; versus prediabetes group.