Association of Androgen Excess with Glucose Intolerance in Women with Polycystic Ovary Syndrome
Table 3
Anthropometric and clinical characteristics of women with PCOS according to tertiles of FAI.
FAI < 3.77
3.77 ≤ FAI < 7.44
FAI ≥ 7.44
99
98
98
-
Age,
29.0 ± 4.8
27.9 ± 4.4
27.0 ± 4.
0.007
BMI, kg/m2
28.6 ± 5.3
29.7 ± 4.6
30.8 ± 5.
0.011
Waist circumference, cm
88.4 ± 16.6
91.0 ± 13.0
95.5 ± 13.6
0.055
Waist-to-hip ratio
0.88 ± 0.09
0.89 ± 0.07
0.91 ± 0.07
0.276
HbA1c, %
5.3 (5.0–5.5)
5.4 (5.1–5.6)
5.5
0.045
Fasting glucose, mmol/L
5.1 ± 0.6
5.2 ± 0.7
5.3 ± 0.8
0.069
30 min glucose, mmol/L
8.2 ± 1.3
8.7 ± 1.4
9.1 ± 1.
<0.001
1 h glucose, mmol/L
8.7 ± 2.1
9.0 ± 2.3
10.0 ± 2.
0.001
2 h glucose, mmol/L
7.4 ± 2.0
7.6 ± 2.0
8.2 ± 2.
0.029
Fasting insulin, uIU/mL
15.2 (9.0–20.9)
19.6
24.9
<0.001
30 min insulin, uIU/mL
106.9 (70.2–159.0)
125.0 (87.9–175.6)
153.7
0.001
1 h insulin, uIU/mL
105.6 (76.1–151.8)
137.3
186.7
<0.001
2 h insulin, uIU/mL
99.2 (70.8–166.6)
115.4 (76.2–208.0)
171.2
0.001
Glucose intolerance, %
31 (31.3)
37 (37.8)
52
0.006
PCOS, polycystic ovary syndrome; FAI, free androgen index; BMI, body mass index. Data are presented as mean ± SD, median (25th–75th interquartile range), or (%). versus FAI < 3.77 group; versus 3.77 ≤ FAI < 7.44 group.
