Glycyrrhizin Suppresses the Growth of Human NSCLC Cell Line HCC827 by Downregulating HMGB1 Level

Figure 3

The protein level of HMGB1 is suppressed by glycyrrhizin. (a) indicates the protein level of HMGB1 in lung tumor tissues from the two groups detected by IHC staining assay, bar = 100 μm. (b) indicates the quantitative results based on IHC staining assay. HMGB1-positive cells were counted in the two groups, respectively. , as compared to the model control by t-test. (c) indicates the protein level of HMGB1 from the three groups by western blot. β-Actin was used as an internal control. value was calculated by t-test between glycyrrhizin treatment and DMSO treatment (model). “NC” represents lung tissue from normal mice. , as compared to the model control.

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