Glycyrrhizin Suppresses the Growth of Human NSCLC Cell Line HCC827 by Downregulating HMGB1 Level

Figure 4

Glycyrrhizin inhibits the phosphorylation of Jak2 and Stat3. The phosphorylation level of Jak2 was detected by western blot in the three experimental groups, respectively. , as compared to the model control (a). The phosphorylation level of Stat3 was detected by western blot in the three experimental groups, respectively. , as compared to the model control (b). -Actin was used as an internal control. value was calculated by t-test between glycyrrhizin treatment and DMSO treatment (model). “NC” represents lung tissue from normal mice. Stars are showing values between model and glycyrrhizin.

(a)

(b)