Research Article

A Sargassum fluitans Borgesen Ethanol Extract Exhibits a Hepatoprotective Effect In Vivo in Acute and Chronic Liver Damage Models

Table 2

Effect of S. fluitans ethanol extract on relative liver weight (RLW) and serum biochemical parameters in five groups of a chronic liver damage model in rats. Results are expressed as means ± SD (n = 6). p-Values: &<0.01 vs. CCl4; <0.001 vs. CCl4; <0.001 vs. control; <0.01 vs. control, according to one-way ANOVA with a Tukey post hoc test.

GROUPsRLW (g)AST (U/L)ALT (U/L)AP(U/L)ALB(g/L)

1. Control2.90 ± 0.0785.33 ± 16.0359.00 ± 9.40120.17 ± 12.672.57 ± 0.14
2. EE2.79 ± 0.0696.33 ± 23.9871.67 ± 8.71117.67 ± 11.312.55 ± 0.09
3. CCl43.19 ± 0.08303.17 ± 38.61194.17 ± 9.83213.33 ± 34.482.20 ± 0.11
4. Sil + CCl42.87 ± 0.11114.50 ± 16.91102.50 ± 10.52157.00 ± 26.862.36 ± 0.22
5. EE + CCl42.88 ± 0.1190.67 ± 5.68103.17 ± 14.84157.67 ± 26.752.53 ± 0.15&