Impact of Early versus Late Initiation of Renal Replacement Therapy in Patients with Cardiac Surgery-Associated Acute Kidney Injury: Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials

Table 3

Secondary outcomes of early versus late RRT in patients with AKI after cardiac surgery.

Reference (year)	ICU LOS (days)		Hospital LOS (days)
	Early RRT	Late RRT	Early RRT	Late RRT
Durmaz 2003 [10]	1.6 ± 0.9	3.6 ± 2.9	8.9 ± 2.6	11.7 ± 4.8
Sugahara 2004 [11]	NR	NR	NR	NR
Crescenzi 2015 [12]	2.6 ± 5.5	2.2 ± 3.4	8.6 ± 7.7	8.2 ± 5.5
Combes 2015 [13]	NR	NR	NR	NR

Data are reported as mean ± standard deviation or median. RRT =renal replacement therapy, AKI=acute kidney injury, ICU=intensive care unit, LOS=length of stay, and NR= not reported.