HBV Upregulates CtBP2 Expression via the X Gene

Figure 4

Effect of the HBV X gene on CtBP2 mRNA and protein expression. (a) CtBP2 mRNA expression was detected by RT-qPCR 48 h after transfection of different doses of the X gene eukaryotic expression plasmid pCMV-X (0 μg, 0.5 μg, 1 μg, and 2 μg) into HepG2 cells. (b) CtBP2 protein expression was detected by western blotting 48 h after transfection of different doses of the X gene eukaryotic expression plasmid pCMV-X (0 μg, 0.5 μg, 1 μg, and 2 μg) into HepG2 cells. (c) Correlation between HBx and CtBP2 expression in HBV-related HCC tissues.

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