Review Article

Boosting Secondary Metabolite Production and Discovery through the Engineering of Novel Microbial Biosensors

Figure 2

Metagenomics has become an important tool to improve and expand NP discovery from DNA retrieved from the microbial community inhabitants of environmental samples. Novel genetic parts (structural genes, regulators, terminators, peptide signals, transporters, etc.) are provided, which, when rewired, allow the creation of novel complex bioactive molecules.