Difference between the Upper and the Lower Gastrointestinal Bleeding in Patients Taking Nonvitamin K Oral Anticoagulants

Table 3

Cases of major gastrointestinal bleeding in patients taking direct oral anticoagulants.

Age, sex	NOAC	Lesion	Prescription (month)	BARC	Other factors
Upper GI
92 F	D	Gastric ulcer	11	3a	PPI (-)
96 F	R	Gastric ulcer	42	3a	PPI (-)
63 M	R	Duodenal ulcer	29	3b	PPI (-)
74 M	R	Gastric ulcer	32	3a	PPI (-)
83 F	A	Gastric ulcer	16	3a	PPI (-)
84 M	A	Ulcer; s/o	12	3a	PPI (-), steroid
72 M	A	Duodenal ulcer	25	3b	PPI (-), operation
Lower GI
78 M	D	Ileal erosion	23	3a	DAPT
80 M	D	Colon diverticulosis	7	3a	-
72 F	R	Colon vascular ectasia	8	3a	NSAID, steroid
75 M	R	Post EMR for colon polyp	24	3a	LDA
85 F	A	Colon diverticulosis	3	3b	NSAID

Major bleeding means bleeding greater than Bleeding Academic Research Consortium classification type 3. NOAC: nonvitamin K oral administrative drugs, F: female, M: male, GI, gastrointestinal, D: dabigatran, R: rivaroxaban, A: apixaban, PPI: proton pump inhibitor, DAPT: double antiplatelet therapy, EMR: endoscopic mucosal resection, and NSAID: nonsteroidal anti-inflammatory drug.