Mass Spectrometry-Based Comprehensive Analysis of Pancreatic Cyst Fluids

Figure 3

Sequence Logo plots depicting protease specificity. Positions flanking the N- and C-terminal sides of the cleavage site are named according to standard protease nomenclature, where the cleavage takes place between P1 and P1’[12]. The information content of the position is expressed in bits. Amino acids are represented in one-letter code and coloured according to their physicochemical characteristics: polar, green, hydrophobic, orange, basic, blue, acidic, red. CA, carcinoma; SCN, serous cystic neoplasm; MCN, mucinous cystic neoplasm; IPMN, intraductal papillary mucinous neoplasm; PC, pseudocyst.