Why They Are Different: Based on the Burden of Disease Research of WHO and Institute for Health Metrics and Evaluation

Table 1

Update of DisMod-MR.

DisMod-2	DisMod-MR	DisMod MR 2.0
(i) Parametric assumption with single number; (ii) Needing more flexible model for estimation; (iii) Adjusted covariate variables; (iv) Lack of meta-analysis, Bayesian inference, regression	(i) Bayesian analysis; (a) Flexible model; (b) Markov Chain Monte Carlo for hierarchical model; (c) Availability of uncertainty interval; (ii) Meta-analysis: global, regional fit; (iii) Regression: adjusted age, comorbidity, etc.; (iv) UI of “p X RR”; (v) Adjusting the local fit using global fit with cascade	Faster than DisMod-MR of calculation