Effect of Repeated Injection of Iodixanol on Renal Function in Healthy Wistar Rats Using Functional MRI

Table 2

values changes in 4 renal regions in all groups over time (s⁻¹).

Kidney tissue	Treatment	Baseline	1 h	1 d	3 d	5 d	10 d
CO	1-day subgroup	29.95 ± 2.01	35.75 ± 5.70	35.00 ± 5.82	34.56 ± 5.38	33.70 ± 3.88	32.48 ± 1.61
	3-day subgroup	29.48 ± 1.64	33.75 ± 4.70	33.14 ± 4.28	32.86 ± 4.18	32.24 ± 2.58	30.83 ± 4.20
	5-day subgroup	28.55 ± 3.21	33.25 ± 4.91	32.85 ± 5.17	32.23 ± 3.42	31.36 ± 3.10	29.63 ± 3.41
	Group 1	30.03 ± 1.82	33.95 ± 4.66	33.03 ± 4.07	32.31 ± 3.18	31.05 ± 1.03	30.40 ± 1.38
	Control group	30.36 ± 2.31	29.79 ± 3.61	30.69 ± 2. 72	29.36 ± 3.94	30.83 ± 2.20	29.65 ± 6.07
OSOM	1-day subgroup	33.53 ± 3.06	38.72 ± 4.87	38.12 ± 4.50	37.04 ± 3.02	35.95 ± 2.91	34.57 ± 3.62
	3-day subgroup	33.14 ± 2.36	37.94 ± 6.22	36.79 ± 3.12	36.11 ± 1.63	35.14 ± 4.78	33.50 ± 5.77
	5-day subgroup	31.86 ± 4.40	36.09 ± 1.80	35.23 ± 1.90	33.17 ± 4.21	32.41 ± 1.47	31.94 ± 4.25
	Group 1	34.28 ± 2.69	37.04 ± 3.20	36.31 ± 2.17	35.02 ± 4.75	34.48 ± 2.06	33.63 ± 4.24
	Control group	31.72 ± 5.62	32.30 ± 2.48	32.97 ± 3.50	32.36 ± 2.65	32.54 ± 1.94	33.25 ± 2.46
ISOM	1-day subgroup	35.39 ± 3.55	40.83 ± 4.70	39.05 ± 5.18	38.02 ± 2.21	37.87 ± 1.09	35.68 ± 4.95
	3-day subgroup	34.99 ± 2.59	40.18 ± 1.43	38.17 ± 4.00	37.33 ± 1.80	36.73 ± 1.10	34.68 ± 3.58
	5-day subgroup	33.19 ± 1.89	37.68 ± 4.27	36.90 ± 4.22	36.14 ± 3.53	35.13 ± 2.99	34.10 ± 2.20
	Group 1	35.24 ± 1.63	37.78 ± 1.47	37.40 ± 2.89	37.02 ± 2.68	36.29 ± 2.75	34.57 ± 1.81
	Control group	33.60 ± 2.79	33.11 ± 3.82	34.25 ± 4.12	34.32 ± 3.91	34.05 ± 4.77	35.07 ± 1.80
IM	1-day subgroup	29.59 ± 3.60	34.08 ± 5.64	32.99 ± 3.23	32.08 ± 2.84	31.52 ± 2.44	30.72 ± 4.40
	3-day subgroup	29.23 ± 3.87	33.66 ± 5.09	32.15 ± 4.19	31.59 ± 3.81	31.24 ± 5.77	30.03 ± 2.65
	5-day subgroup	28.34 ± 3.62	33.07 ± 4.69	32.01 ± 6.36	31.72 ± 5.54	30.32 ± 2.18	29.25 ± 3.00
	Group 1	28.53 ± 3.13	33.34 ± 4.45	30.96 ± 3.73	30.17 ± 2.66	29.68 ± 1.35	28.14 ± 2.57
	Control group	29.27 ± 3.24	28.87 ± 2.23	29.45 ± 3.60	28.69 ± 2.66	29.61 ± 2.75	28.49 ± 2.21

versus baseline; versus Group 1.