Exhaled Nitric Oxide and Exhaled Breath Temperature as Potential Biomarkers in Patients with Pulmonary Hypertension
Table 2
Right-heart catheterization and pulmonary function data of patients studied.
Group A (PHA)
Group B (COPD)
Group C (HF)
p
Mean PAP (mm Hg)
35.5 (8.3)
38.2 (8.3)
59.3 (24)
0.011
32.5 (28-53)
37 (23-47)
65 (33-80)
Systolic PAP (mm Hg)
72.7 (21.1)
81.7 (22.3)
101.6 (18.9)
0.158
70 (48-105)
83 (50-113)
110 (80-115)
CI (l/min)
2.98 (0.88)
2.89 (0.79)
3.33 (0.57)
0.710
2.98 (2-5)
2.8 (1-4)
3 (3-4)
Pulmonary capillary wedge pressure (mm Hg)
13 (4.6)
14.5 (4.4)
16 (1.4)
0.598
13 (8-22)
14 (10-22)
15 (17-21)
Pulmonary vascular resistance (WU)
4.7 (2.2)
5.1(3.8)
4.8 (1.8)
0.478
5.7 (1.8-8.3)
3.6(1.7-11.3)
5 (1.8-10)
Right atrial pressure (mm Hg)
8.5 (3.6)
10.2 (2.1)
9.5 (2.2)
0.256
9 (2-13)
9 (8-13)
9 (5-16)
FEV1 (L)
1.9 (8.85)
1.5 (0.43)
1.13 (0.27)
0.197
1.7 (1-3.5)
1.5 (0.79-1.9)
1 (0.9-1.43)
FEV1 (%predicted)
76.7 (17.2)
58.5 (15.9)
57.3 (4.5)
0.071
81 (55-105)
65 (31-74)
57 (53-62)
FVC (L)
2.55 (1.1)
2.9 (1)
1.4 (045)
0.158
2.4 (1.1-4.8)
2.8 (1.3-4.4)
1.3 (1-1.9)
FVC (% predicted)
82.5 (21.5)
82.8 (19.4)
59.6 (7.6)
0.195
85 (50-118)
76 (57-120)
58 (53-68)
FEV1/FVC
74.3 (12.4)
54.6 (11.8)
79.6 (16)
0.007
73 (53-93)
54 (35-71)
73 (68-98)
DLCO (%predicted)
37.7 (12.4)
41.4 (13.6)
71.6 (7.6)
0.003
36 (24-59)
44 (23-63)
70 (65-80)
6MWD (meters)
336 (140.3)
355.3 (153)
278.3 (158.5)
0.881
299(160-497)
391(100-520)
207(100-520)
Data reported as mean (standard deviation) and median (minimum-maximum). PAP: pulmonary artery pressure; CI: cardiac index; WU: wood units; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; DLCO: carbon monoxide diffusion; 6MWD: six-minute walking distance; n.s.: not significant; and p: p value among the groups studied (ANOVA)
