CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging

Table 3

Static dual-energy CTP imaging.

Author; (Year)	Patients No.	CT; Scanner	CTP Protocol	Stress Agent; (dose)	Analysis	Reference; Standard	SE (%)	SP (%)	PPV (%)	NPV (%)	Dose
Ko et al [65]; (2012)	45	DS (1st)		Adenosine; (0.14 mg/kg/min)	Iodine Map; (for vessel)	QCA	89	74	80	85	5.7; mSv
Meinel et al [66]; (2014)	55	DS (2nd)		Adenosine; (0.14 mg/kg/min); Regadenoson (0.4 mg)	Iodine Map; (for segment)	SPECT	99	97	92	100	7.1; mSv
Delgado et al [67]; (2013)	56	DS (2nd)		Adenosine; (0.14 mg/kg/min)	Iodine Map; (for segment)	MRI 1.5T	76	99	89	98	5.2; mSv
Kido et al [68]; (2014)	21	DS; (1st-2nd)		Adenosine; (0.16 mg/kg/min)	Iodine Map; (for vessel)^§	QCA	67	92	84	82	7.7; mSv
Kim et al [69]; (2014)	50	DS (2nd)		Adenosine; (0.14 mg/kg/min)	Iodine Map; (for segment)	MRI 1.5T	77	94	53	98	6.5; mSv
Ko et al [70]; (2014)	40	DS (1st)		Adenosine; (0.14 mg/kg/min)	Iodine Map; (for vessel)	QCA + MRI 3T^§	87	79	71	91	4.6; mSv
Ko et al [71]; (2014)	100	DS (1st)		Adenosine; (0.14 mg/kg/min)	Iodine Map; (for vessel)	QCA + MRI 1.5T and 3T^§	88	79	73	91	4.2; mSv

CTP, computed tomography perfusion; 1st and 2nd, first and second generation; CT, computed tomography; DS, Dual-Source scanner; CCTA, coronary computed tomography angiography; DECT, dual-energy computed tomography; SECT, single-energy computed tomography; RETROSP, retrospective ECG-gating acquisition; NA, nonassessable; MRI, magnetic resonance imaging; No., patients’ number; NPV, negative predictive value; PPV, positive predictive value; QCA, quantitative coronary angiography; SE, sensitivity; SP, specificity; SPECT, myocardial perfusion scan; ^§, accuracy of CT perfusion integrated with the coronary anatomic data.