Research Article

The Correlations of Plasma and Cerebrospinal Fluid Amyloid-Beta Levels with Platelet Count in Patients with Alzheimer’s Disease

Table 1

Characteristics of the study population.

CON (n=61)AD (n=58)PIB-PET(+)-AD (n=18)P1 value (AD vs. CON)P2 value (PET vs. CON)

Age (years)69.16±11.5571.52±10.7168.22±8.000.2520.748
Female (%)30 (49.18)30 (51.72)9 (50.00)0.7810.951
Education years9.13±3.587.89±4.429.56±4.590.2250.550
Hypertension (%)14 (22.95)11 (18.97)3 (16.67)0.5940.807
Diabetes mellitus (%)2 (3.28)4 (6.90)00.629>0.999
Cardiovascular disease (%)9 (14.75)5 (8.62)1 (5.56)0.2990.530
Hyperlipidemia (%)5 (8.20)4 (6.90)0>0.9990.481
Platelet count162.57±53.00168.97±44.32178.22±53.400.4780.275
MMSE27.17±2.7516.48±6.5112.17±5.76<0.001<0.001
CDR01.86±0.862.08±0.88<0.001<0.001

Data given as mean ± SD unless otherwise stated. MMSE, Minimental State Examination; CDR, Clinical Dementia Rating. P value, two-tailed independent t-tests, Mann-Whitney U test, or Chi-square test as appropriate.