Electroporation with Cisplatin against Metastatic Pancreatic Cancer: In Vitro Study on Human Primary Cell Culture

Table 3

The results of immunocytochemical staining for the reactivity with mitochondrial superoxide dismutase (SOD-2) and the apoptotic marker caspase 3 (Casp-3) on human primary cell culture derived from PDA pulmonary metastases.

Electric field strength	Cisplatin concentration [µM]	SOD-2		Casp-3
		Staining intensity	% of stained cells	Staining intensity	% of stained cells
0 V/cm	0	+	100	−/+	22
	5	+/++	100	+	78
	10	+/++	100	+/++	97
600 V/cm	0	+/++	100	+	96
	5	+/++	100	++	98
	10	+/++	100	++/+++	97
1000 V/cm	0	++	100	+	90
	5	++/+++	100	++/+++	100
	10	+++	100	++/+++	100