Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2018, Article ID 7375831, 18 pages
https://doi.org/10.1155/2018/7375831
Review Article

Health Risk Behaviour among Adolescents Living with HIV in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

1Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute (KEMRI), P.O. Box 230, Kilifi, Kenya
2Utrecht Centre for Child and Adolescent Studies, Utrecht University, P.O. Box 80140, 3508 TC Utrecht, Netherlands
3Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford OX3 7JX, UK
4Department of Public Health, Pwani University, P.O. Box 195, Kilifi, Kenya

Correspondence should be addressed to Derrick Ssewanyana; gro.emocllew-irmek@anaynawessd

Received 30 August 2017; Revised 10 November 2017; Accepted 14 December 2017; Published 28 January 2018

Academic Editor: Marcelo A. Soares

Copyright © 2018 Derrick Ssewanyana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Crepaz, C. M. Lyles, R. J. Wolitski et al., “Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials,” AIDS, vol. 20, no. 2, pp. 143–157, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. The Joint United Nations Programme on HIV and AIDS (UNAIDS), "The Gap Report," 2014, http://www.unaids.org/en/resources/documents/2014/20140716_UNAIDS_gap_report.
  3. Center for Disease Control and Prevention (CDC), "Adolescent and School Health," 2015, http://www.cdc.gov/healthyyouth/data/yrbs/overview.htm.
  4. C. Currie, C. Zanotti, and A. Morgan, “Health Behaviour in School-aged Children (HBSC) study: international report from the 2009/2010 survey,” Tech. Rep., WHO Regional Office for Europe, 2012, http://www.euro.who.int/__data/assets/pdf_file/0003/163857/Social-determinants-of-health-and-well-being-among-young-people.pdf. View at Google Scholar
  5. L. Steinberg, “A social neuroscience perspective on adolescent risk-taking,” Developmental Review, vol. 28, no. 1, pp. 78–106, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Bakeera-Kitaka, N. Nabukeera-Barungi, C. Nöstlinger, K. Addy, and R. Colebunders, “Sexual risk reduction needs of adolescents living with HIV in a clinical care setting,” AIDS Care Psychological and Socio-medical Aspects of AIDS/HIV, vol. 20, no. 4, pp. 426–433, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Nöstlinger, G. Bartoli, V. Gordillo, D. Roberfroid, and R. Colebunders, “Children and adolescents living with HIV positive parents: emotional and behavioural problems,” Vulnerable Children and Youth Studies, vol. 1, no. 1, pp. 29–43, 2006. View at Publisher · View at Google Scholar
  8. D. A. Murphy, S. J. Durako, A.-B. Moscicki et al., “No change in health risk behaviors over time among HIV infected adolescents in care: Role of psychological distress,” Journal of Adolescent Health, vol. 29, no. 3, pp. 57–63, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Tassiopoulos, A.-B. Moscicki, C. Mellins et al., “Sexual risk behavior among youth with perinatal HIV infection in the United States: predictors and implications for intervention development,” Clinical Infectious Diseases, vol. 56, no. 2, pp. 283–290, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. C. A. Mellins, K. S. Elkington, and J. A. Bauermeister, “Sexual and drug use behavior in perinatally HIV- infected youth: Mental health and family influences,” Journal of the American Academy of Child Adolescent Psychiatry, vol. 48, no. 8, pp. 810–819, 2009. View at Publisher · View at Google Scholar
  11. L. Gavin, C. Galavotti, H. Dube et al., “Factors Associated with HIV Infection in Adolescent Females in Zimbabwe,” Journal of Adolescent Health, vol. 39, no. 4, pp. 596–e18, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. H. B. Jaspan, J. R. Berwick, L. Myer et al., “Adolescent HIV Prevalence, Sexual Risk, and Willingness to Participate in HIV Vaccine Trials,” Journal of Adolescent Health, vol. 39, no. 5, pp. 642–648, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Jewkes, K. Dunkle, M. Nduna et al., “Factors associated with HIV sero-positivity in young, rural South African men,” International Journal of Epidemiology, vol. 35, no. 6, pp. 1455–1460, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. F. S. Test, S. D. Mehta, A. Handler, E. Mutimura, A. M. Bamukunde, and M. Cohen, “Gender inequities in sexual risks among youth with HIV in Kigali, Rwanda,” International Journal of STD & AIDS, vol. 23, no. 6, pp. 394–399, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. K. Hein, R. Dell, D. Futterman, M. J. Rotheram-Borus, and N. Shaffer, “Comparison of HIV+ and HIV - adolescents: Risk factors and psychosocial determinants,” Pediatrics, vol. 95, no. 1, pp. 96–104, 1995. View at Google Scholar · View at Scopus
  16. M. A. Chesney, “Factors affecting adherence to antiretroviral therapy,” Clinical Infectious Diseases, vol. 30, no. 2, pp. S171–S176, 2000. View at Publisher · View at Google Scholar · View at Scopus
  17. G. Chander, B. Lau, and R. D. Moore, “Hazardous alcohol use: a risk factor for non-adherence and lack of suppression in HIV infection,” Journal of Acquired Immune Deficiency Syndromes, vol. 43, no. 4, pp. 411–417, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. R. D. LaGrange, S. J. Mitchell, M. Lewis, S. Abramowitz, and L. J. D'Angelo, “Health protective behaviors among young people living with HIV/AIDS,” Journal of AIDS & Clinical Research, vol. 3, no. 1, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. S. C. Kalichman, J. Pellowski, and C. Turner, “Prevalence of sexually transmitted co-infections in people living with HIV/AIDS: systematic review with implications for using HIV treatments for prevention,” Sexually Transmitted Infections, vol. 87, no. 3, pp. 183–190, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Danta, D. Brown, S. Bhagani et al., “Recent epidemic of acute hepatitis C virus in HIV-positive men who have sex with men linked to high-risk sexual behaviours,” AIDS, vol. 21, no. 8, pp. 983–991, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Helleberg, S. Afzal, G. Kronborg et al., “Mortality attributable to smoking among HIV-1-infected individuals: a nationwide, population-based cohort study,” Clinical Infectious Diseases, vol. 56, no. 5, pp. 727–734, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. W. Masanjala, “The poverty-HIV/AIDS nexus in Africa: A livelihood approach,” Social Science & Medicine, vol. 64, no. 5, pp. 1032–1041, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. I. J. Birdthistle, S. Floyd, A. MacHingura, N. Mudziwapasi, S. Gregson, and J. R. Glynn, “From affected to infected? Orphanhood and HIV risk among female adolescents in urban Zimbabwe,” AIDS, vol. 22, no. 6, pp. 759–766, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. D. Swendeman, M. J. Rotheram-Borus, S. Comulada, R. Weiss, and M. E. Ramos, “Predictors of HIV-related stigma among young people living with HIV,” Health Psychology, vol. 25, no. 4, pp. 501–509, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. S. Clark, “Early marriage and HIV risks in sub-Saharan Africa,” Studies in Family Planning, vol. 35, no. 3, pp. 149–160, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. G. Nakigozi, L. Atuyambe, M. Kamya et al., “A qualitative study of barriers to enrollment into free HIV care: Perspectives of never-in-care HIV-positive patients and providers in Rakai, Uganda,” BioMed Research International, vol. 2013, Article ID 470245, 7 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. G. Foster and J. Williamson, “A review of current literature on the impact of HIV/AIDS on children in sub-Saharan Africa,” AIDS, vol. 14, supplement 3, pp. S275–S284, 2000. View at Google Scholar · View at Scopus
  28. P. Anand, S. A. Springer, M. M. Copenhaver, and F. L. Altice, “Neurocognitive impairment and HIV risk factors: a reciprocal relationship,” AIDS and Behavior, vol. 14, no. 6, pp. 1213–1226, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. H. Aboki, M. O. L. Folayan, U. Daniel'and, and M. Ogunlayi, “Changes in sexual risk behavior among adolescents: is the HIV prevention programme in Nigeria yielding results?” African Journal of Reproductive Health, vol. 18, no. 3, pp. 109–117, 2014. View at Google Scholar · View at Scopus
  30. B. Auvert, R. Ballard, C. Campbell et al., “HIV infection among youth in a South African mining town is associated with herpes simplex virus-2 seropositivity and sexual behaviour,” AIDS, vol. 15, no. 7, pp. 885–898, 2001. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Birungi, F. Obare, J. F. Mugisha, H. Evelia, and J. Nyombi, “Preventive service needs of young people perinatally infected with HIV in Uganda,” AIDS Care, vol. 21, no. 6, pp. 725–731, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. R. Bunnell, A. Opio, J. Musinguzi et al., “HIV transmission risk behavior among HIV-infected adults in Uganda: Results of a nationally representative survey,” AIDS, vol. 22, no. 5, pp. 617–624, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. R. Jewkes, K. Dunkle, M. Nduna et al., “Factors associated with HIV sero-status in young rural South African women: Connections between intimate partner violence and HIV,” International Journal of Epidemiology, vol. 35, no. 6, pp. 1461–1468, 2006. View at Publisher · View at Google Scholar · View at Scopus
  34. T. Lane, A. Pettifor, S. Pascoe, A. Fiamma, and H. Rees, “Heterosexual anal intercourse increases risk of HIV infection among young South African men,” AIDS, vol. 20, no. 1, pp. 123–125, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. A. Mhalu, G. H. Leyna, and E. J. Mmbaga, “Risky behaviours among young people living with HIV attending care and treatment clinics in Dar Es Salaam, Tanzania: Implications for prevention with a positive approach,” Journal of the International AIDS Society, vol. 16, Article ID 17342, 2013. View at Publisher · View at Google Scholar · View at Scopus
  36. A. E. Steffenson, A. E. Pettifor, G. R. Seage, H. V. Rees, and P. D. Cleary, “Concurrent sexual partnerships and human immunodeficiency virus risk among South African youth,” Sexually Transmitted Diseases, vol. 38, no. 6, pp. 459–466, 2011. View at Publisher · View at Google Scholar · View at Scopus
  37. J. K. Konde-Lule, M. J. Wawer, N. K. Sewankambo et al., “Adolescents, sexual behavior and HIV-1 in rural Rakai district, Uganda,” AIDS, vol. 11, no. 6, pp. 791–799, 1997. View at Publisher · View at Google Scholar · View at Scopus
  38. United Nations International Children's Fund (UNICEF), "Opportunity in Crisis: Preventing HIV from early adolescence to young adulthood," 2011 https://www.unicef.org/publications/index_58708.html.
  39. United Nations (UN), "Youth population trends and sustainable development," 2015 http://www.un.org/en/development/desa/population/publications/factsheets/.
  40. S. M. Sawyer, S. Drew, M. S. Yeo, and M. T. Britto, “Adolescents with a chronic condition: challenges living, challenges treating,” The Lancet, vol. 369, no. 9571, pp. 1481–1489, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. J. M. Zweig, L. D. Lindberg, and K. A. McGinley, “Adolescent health risk profiles: The co-occurrence of health risks among females and males,” Journal of Youth and Adolescence, vol. 30, no. 6, pp. 707–728, 2001. View at Publisher · View at Google Scholar · View at Scopus
  42. D. Moher, A. Liberati, J. Tetzlaff, D. G. Altman, and The PRISMA Group, “Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement,” Annals of Internal Medicine, vol. 151, no. 4, pp. 264–269, 2009. View at Publisher · View at Google Scholar
  43. W. C. W. Wong, C. S. K. Cheung, and G. J. Hart, “Development of a quality assessment tool for systematic reviews of observational studies (QATSO) of HIV prevalence in men having sex with men and associated risk behaviours,” Emerging Themes in Epidemiology, vol. 5, article 23, 2008. View at Publisher · View at Google Scholar · View at Scopus
  44. V. N. Nyaga, M. Arbyn, and M. Aerts, “Metaprop: A Stata command to perform meta-analysis of binomial data,” Archives of Public Health, vol. 72, no. 1, pp. 1–10, 2014. View at Publisher · View at Google Scholar · View at Scopus
  45. G. Marks, N. Crepaz, J. W. Senterfitt, and R. S. Janssen, “Meta-analysis of high-risk sexual behavior in persons aware and unaware they are infected with HIV in the United States: Implications for HIV prevention programs,” Journal of Acquired Immune Deficiency Syndromes, vol. 39, no. 4, pp. 446–453, 2005. View at Publisher · View at Google Scholar · View at Scopus
  46. J. Seeley, J. Nakiyingi-Miiro, A. Kamali et al., “High HIV incidence and socio-behavioral risk patterns in fishing communities on the shores of Lake Victoria, Uganda,” Sexually Transmitted Diseases, vol. 39, no. 6, pp. 433–439, 2012. View at Publisher · View at Google Scholar · View at Scopus
  47. C. N. Morris and A. G. Ferguson, “Sexual and treatment-seeking behaviour for sexually transmitted infection in long-distance transport workers of East Africa,” Sexually Transmitted Infections, vol. 83, no. 3, pp. 242–245, 2007. View at Publisher · View at Google Scholar · View at Scopus
  48. World Health Organization, "Health for the World's Adolescents. A second chance in the second decade." 2014 http://apps.who.int/adolescent/seconddecade/files/1612_MNCAH_HWA_Executive_Summary.pdf.
  49. J. Wamoyi, K. Stobeanau, N. Bobrova, T. Abramsky, and C. Watts, “Transactional sex and risk for HIV infection in sub-Saharan Africa: a systematic review and meta-analysis,” Journal of the International AIDS Society, vol. 19, no. 1, p. 20992, 2016. View at Publisher · View at Google Scholar · View at Scopus
  50. A. M. Moore, K. Awusabo-Asare, N. Madise, J. John-Langba, and A. Kumi-Kyereme, “Coerced first sex among adolescent girls in sub-Saharan Africa: prevalence and context.,” African Journal of Reproductive Health, vol. 11, no. 3, pp. 62–82, 2007. View at Publisher · View at Google Scholar · View at Scopus
  51. L. Cluver, M. Orkin, M. Boyes, F. Gardner, and F. Meinck, “Transactional sex amongst AIDS-orphaned and AIDS-affected adolescents predicted by abuse and extreme poverty,” Journal of Acquired Immune Deficiency Syndromes, vol. 58, no. 3, pp. 336–343, 2011. View at Publisher · View at Google Scholar · View at Scopus
  52. M. R. Tanney, S. Naar-King, D. A. Murphy, J. T. Parsons, and H. Janisse, “Multiple Risk Behaviors Among Youth Living with Human Immunodeficiency Virus in Five U.S. Cities,” Journal of Adolescent Health, vol. 46, no. 1, pp. 11–16, 2010. View at Publisher · View at Google Scholar · View at Scopus
  53. E. G. Bing, M. A. Burnam, D. Longshore et al., “Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States,” Archives of General Psychiatry, vol. 58, no. 8, pp. 721–728, 2001. View at Publisher · View at Google Scholar · View at Scopus
  54. K. Fritz, N. Morojele, and S. Kalichman, “Alcohol: The forgotten drug in HIV/AIDS,” The Lancet, vol. 376, no. 9739, pp. 398–400, 2010. View at Publisher · View at Google Scholar · View at Scopus
  55. K. E. Leonard, “Alcohol and intimate partner violence: When can we say that heavy drinking is a contributing cause of violence?” Addiction, vol. 100, no. 4, pp. 422–425, 2005. View at Publisher · View at Google Scholar · View at Scopus
  56. L. Slaughter, “Involvement of drugs in sexual assault,” Obstetrics, Gynaecology and Reproductive Medicine, vol. 45, no. 5, pp. 425–430, 2000. View at Google Scholar · View at Scopus
  57. R. J. Fisher, “Social desirability bias and the validity of indirect questioning,” Journal of Consumer Research, vol. 20, no. 2, pp. 303–315, 1993. View at Publisher · View at Google Scholar