Research Article
Comparative Proteomic Study of the Antiproliferative Activity of Frog Host-Defence Peptide Caerin 1.9 and Its Additive Effect with Caerin 1.1 on TC-1 Cells Transformed with HPV16 E6 and E7
Figure 1
Caerin 1.1 and caerin 1.9 are able to inhibit the proliferation of TC-1 cells but not NP-69 cells, measured by MTT assay. (a) 1 × 105 of TC-1 cells and (b) 1 × 105 of NP-69 cells were cultured either in media alone or with different concentrations (15, 10, 8, 5, and 1 μg/mL) of caerin 1.1, caerin 1.9, or P3 for 24 hours before MTT assay was performed. Inhibition magnitude (in percentage) in comparison with untreated cells was shown above or on the bars. Each bar represents the statistical mean from three biological replicates (performed in triplicate) and the error bars represent the standard deviation.
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