Antidepressant-Like and Neuroprotective Effects of Ethanol Extract from the Root Bark of Hibiscus syriacus L.

Figure 7

Effects of HSR on protein expression of BDNF, CREB, and MAPKs in corticosterone-treated SK-N-SH cells. (a) Western blotting analysis and (b) intensity of protein bands were quantified by densitometry. Total CREB, ERK, JNK, p38, and β-actin were used as internal standards. The data are representative of three independent experiments. Data are the mean ± SD (n = 3). p < 0.001 and p < 0.0001 vs. the normal group; p < 0.05, p < 0.001, and p < 0.0001 vs. the control group.

(a)

(b)