Bioconversion of -Tyrosol into Hydroxytyrosol under Bench-Scale Fermentation

Table 1

Experimental design and results of the bioconversion of tyrosol into hydroxytyrosol. Numbers between parentheses represent the coded values of both studied variables.

Experiment	Biomass (g/L)	Tyrosol (g/L)	Hydroxytyrosol production (mM)		Residual hydroxytyrosol production (mM)
			Observed	Predicted
1	5.00 (+1)	6.00 (+1)	34.91	35.92	-1.017
2	5.00 (+1)	6.00 (+1)	37.39	35.92	1.462
3	5.00 (+1)	5.00 (0)	29.88	29.93	-0.056
4	5.00 (+1)	5.00 (0)	29.48	29.93	-0.454
5	5.00 (+1)	4.00 (-1)	20.75	21.09	-0.343
6	5.00 (+1)	4.00 (-1)	21.50	21.09	0.408
7	3.75 (0)	6.00 (+1)	33.61	33.22	0.387
8	3.75 (0)	6.00 (+1)	32.39	33.22	-0.832
9	3.75 (0)	5.00 (0)	28.87	28.67	0.195
10	3.75 (0)	5.00 (0)	28.61	28.67	-0.064
11	3.75 (0)	4.00 (-1)	20.66	21.27	-0.614
12	3.75 (0)	4.00 (-1)	22.20	21.27	0.928
13	2.50 (-1)	5.00 (0)	30.9	29.96	0.934
14	2.50 (-1)	5.00 (0)	29.41	29.96	-0.555
15	2.50 (-1)	4.00 (-1)	23.73	24.00	-0.274
16	2.50 (-1)	4.00 (-1)	23.9	24.00	-0.104
17	2.50 (-1)	6.00 (+1)	-	-	-
18	2.50 (-1)	6.00 (+1)	-	-	-