Research Article
Genetic Polymorphism in the RYR1 C6487T Is Associated with Severity of Hypospadias in Chinese Han Children
Table 2
Distribution frequencies of genotypes and alleles on the C6487T in the RYR1 gene.
| | Genotypes | Case group
(n = 263) | Control group (n = 312) | P | OR | 95% CI | | (%) | (%) |
| | CC | 130 (49.43) | 203 (65.06) | | | Reference | | CT | 102 (38.78) | 91 (29.17) | 0.002 | 1.75 | 1.223-2.505 | | TT | 31 (11.79) | 18 (5.77) | 0.001 | 2.689 | 1.445-5.006 | | CT + TT | 133 (50.57) | 109 (34.94) | 0.002 | 1.905 | 1.362-2.665 | | C allele | 362 (68.82) | 497 (79.65) | | | Reference | | T allele | 164 (31.18) | 127 (20.35) | < 0.001 | 1.773 | 1.356-2.319 |
|
|
OR, odds ratio; CI, confidence intervals.
|
