Research Article

Morphological Predictive Features on Spectral-Domain Optical Coherence Tomography for Visual Outcomes in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab

Table 1

Patient demographic and baseline characteristics.

GroupP-value
“Responders”“Nonresponders”
(n = 40)(n = 24)

Age at first injection,
years (mean ± SD)
81.3 ± 2.676.2 ± 4.20.30
Sex, n (%)
Male15 (37.5)6 (25.0)0.33
Female25 (62.5)18 (75.0)0.29
Best-corrected visual acuity, ETDRS (mean ± SD)58 ± 8.061 ± 7.20.27
Central retinal thickness,
μm (mean ± SD)
368.7 ± 87.2376.0 ± 141.10.80
CNV type on FA, n (%)
Type 1 CNV20 (50.0)16 (66.7)0.37
Type 2 CNV10 (25.0)4 (16.7)0.28
Type 3 CNV5 (12.5)2 (8.3)0.42
Type 4 CNV5 (12.5)2 (8.3)0.42

n, number; SD, standard deviation; y, years; ETDRS, Early Treatment Diabetic Retinopathy Study; CNV, choroidal neovascularization; FA, fluorescein angiography; Type 1 CNV, sub-RPE (retinal pigment epithelium) CNV; Type 2, subretinal CNV; Type 3, intraretinal CNV; Type 4, Mixed CNV.