Artificial Liver and Renal Support System for Cynomolgus Monkeys with Surgery-Induced Acute Renal Failure: A Preclinical Study

Figure 4

Levels of serum creatinine (SCr) (a), blood urea nitrogen (BUN) (b), creatinine kinase (CK) (c), lactate dehydrogenase (LDH) (d), aspartate aminotransferase (AST) (e), alanine amino transferase (ALT) (f), potassium (K) (g), and activated partial thromboplastin time (APTT) (h) in experimental animals before surgery, after surgery, after 3 h of treatment, and after 6 h of treatment. A -test was used to determine the significance of differences. , before surgery versus after surgery in the treatment group; , after surgery versus 6 h of treatment in the treatment group; , treatment group versus control group after 6 h of treatment; NS, no significant difference.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)