Association of Ki-67 Labelling Index and IL-17A with Pituitary Adenoma

Table 3

Knosp classification of pituitary adenoma [5].

Grade 0	No involvement of the cavernous sinus (normal condition)
Grade 1	The tumor pushes into the medial wall of the cavernous sinus, but does not go beyond a hypothetical line extending between the centers of the two segments of the internal carotid artery (noninvasive PA)
Grade 2	The tumor goes beyond hypothetical line, but without passing a line tangent to the lateral margins of the artery itself (noninvasive PA)
Grade 3	The tumor extends laterally to the internal carotid artery within the cavernous sinus (invasive PA)
Grade 4	Total encasement of the intracavernous carotid artery (invasive PA)