Development of a Novel Diagnostic Biomarker Set for Rheumatoid Arthritis Using a Proteomics Approach

Table 1

Basic demographic and clinical characteristics of the subjects.

	Group	Number of subjects	RF (IU/mL)	Sex (Female/Male)	Anti-CCP (U/mL)	Age (Years)
LC-MS/MS	Healthy	18	6.5 ± 3.7	14/4	1.9 ± 8.1	65.1 ± 14.0
	RA patients	18	75.3 ± 94.6	14/4	124.5 ± 71.8	60.0 ±10.8
ELISA (validation)	Healthy	43	5.8 ± 4.0	29/14	4.9 ± 24.8	60.1 ± 12.9
	RA patients	44	29.9 ± 9.7	37/7	96.1 ± 96.6	59.8 ± 9.0

RF, rheumatoid factor; LC-MS/MS, liquid chromatography-tandem mass spectrometry; ELISA, enzyme-linked immunosorbent assay.
< 18 IU/mL.
Data are expressed as the mean ± SD.