Lysophosphatidic Acid Analogue rather than Lysophosphatidic Acid Promoted the Bone Formation In Vivo

Table 2

The hepatic and renal functions of mice after treatment with LPA or analogues were determined by blood chemistry tests.

Index	Control	LPA	Analogues
TP (g/L)	35.97 ± 0.25	36.10 ± 1.17	35.73 ± 1.43
ALB (g/L)	27.00 ± 2.27	26.80 ± 0.96	26.77 ± 0.74
GLOB (g/L)	9.06 ± 1.55	9.01 ± 1.22	9.17 ± 0.86
A/G	3.09 ± 0.51	3.03 ± 0.38	2.95 ± 0.29
ALT (U/L)	55.00 ± 3.74	53.33 ± 3.57	51.67 ± 5.78
ALP (U/L)	5.07 ± 2.12	5.17 ± 0.17	5.05 ± 0.13
AST (U/L)	104.73 ± 6.70	100.43 ± 3.63	103.33 ± 9.57
BUN (mmol/L)	6.58 ± 0.05	6.50 ± 0.09	6.44 ± 0.12
CRE (μmol/L)	39.13 ± 2.12	37.80 ± 1.61	37.77 ± 3.07

TP: total protein; ALB: albumin; GLOB: globulin; A/G: albumin/globulin ratio; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; BUN: blood urea nitrogen; CRE: creatinine.