Susceptibility of Diabetic Mice to Noise Trauma

Figure 3

Whole mounts of the auditory epithelium from wild-type (A1, A2, and A3) and db/db mice (B1, B2, and B3) at 2 weeks after noise exposure. Tissues were stained for myosin VIIa (red) to identify the hair cells and for NF200 (green) to identify nerve fibers and then observed by epifluorescence microscopy. Hair cell loss was more severe in the middle (B2) and basal turns (B3) of the db/db compared with wild-type mice (A2 and A3). (A1) and (B1): apical turn; (A2) and (B2): middle turn; A3 and B3: basal turn; OHC: outer hair cell; IHC: inner hair cell; scale bar = 30 μm.