Research Article

Inference of Crosstalk Effects between DNA Methylation and lncRNA Regulation in NSCLC

Figure 1

Schematic illustration for MetLnc process and outcomes. The toolkit carries out three main functional processes, namely, DNA methylation profiling preprocess (group-wise patient sample curation and profiling data formatting), information retrieval (CpG annotation, differential methylated CpG loci, and differential lncRNA candidates), and integration (genome-wide comparison and association analysis on the methylation effects).