The Clinical Significance of Changes in the Expression Levels of MicroRNA-1 and Inflammatory Factors in the Peripheral Blood of Children with Acute-Stage Asthma
Table 2
Expression levels of miR-1 and inflammatory factors in peripheral blood.
Groups (disease severity)
N
miR-1
IL-4 (ng/L)
IL-5 (ng/L)
IL-8 (ng/L)
TNF-α (ng/L)
IFN-γ (ng/L)
Control
100
6.49 ± 2.04
75.49 ± 48.53
15.94 ± 4.64
708.60 ± 348.14
175.58 ± 96.51
84.55 ± 16.88
Study (mild)
44
4.05 ± 0.81
77.08 ± 45.60
20.48 ± 13.02
1201.53 ± 687.26
432.74 ± 257.66
70.25 ± 10.95
Study (medium)
39
3.25 ± 1.40
108.55 ± 59.89
28.61 ± 14.68
1592.93 ± 974.32
527.39 ± 327.63
62.60 ± 13.22
Study (severe)
17
0.60 ± 0.51
189.89 ± 14.92
35.54 ± 18.59
2618.91 ± 685.81
913.59 ± 299.64
48.26 ± 8.35
F
88.561
28.268
23.778
55.026
69.847
44.610
P
0.000
0.000
0.001
0.000
0.000
0.000
compared to control; compared to mild; compared to medium. : the value of ANOVA (analysis of variance).
