Association of Initial Serum Total Calcium Concentration with Mortality in Critical Illness

Table 3

Covariates were adjusted as in model I.

		Serum Calcium Levels (mg/dl)
	N	≤7.6	7.7- 8.1	8.2- 8.5	8.6- 9.0	≥9
AKI
No	32930	1.80 (1.60, 2.02)	1.10 (0.98, 1.25)	1.02 (0.91, 1.15)	1.0(ref)	1.16 (1.03, 1.30)
Yes	12056	1.74 (1.53, 1.98)	1.32 (1.15, 1.51)	1.07 (0.93, 1.23)	1.0(ref)	1.08 (0.94, 1.23)
CKD
No	38097	2.03 (1.85, 2.22)	1.24 (1.12, 1.37)	1.03 (0.93, 1.14)	1.0(ref)	1.14 (1.03, 1.25)
Yes	6889	1.71 (1.38, 2.11)	1.30 (1.06, 1.61)	1.10 (0.89, 1.36)	1.0(ref)	1.19 (0.98, 1.44)
Chronic heart failure
No	37208	1.91 (1.74, 2.10)	1.19 (1.08, 1.31)	1.01 (0.91, 1.11)	1.0(ref)	1.14 (1.04, 1.26)
Yes	7778	2.01 (1.62, 2.49)	1.47 (1.19, 1.81)	1.15 (0.93, 1.42)	1.0(ref)	1.17 (0.96, 1.43)
Pneumonia
No	34237	2.18 (1.96, 2.42)	1.29 (1.15, 1.45)	1.01 (0.90, 1.13)	1.0(ref)	1.21 (1.08, 1.35)
Yes	10749	1.49 (1.29, 1.72)	1.14 (0.98, 1.32)	1.08 (0.93, 1.25)	1.0(ref)	1.07 (0.92, 1.24)
Liver disease
No	41826	2.01 (1.83, 2.20)	1.23 (1.12, 1.36)	1.05 (0.95, 1.15)	1.0(ref)	1.12 (1.02, 1.22)
Yes	3160	1.37 (1.05, 1.79)	1.13 (0.86, 1.48)	0.92 (0.68, 1.23)	1.0(ref)	1.29 (0.99, 1.69)
Acute pancreatitis
No	43954	1.95 (1.79, 2.13)	1.24 (1.13, 1.35)	1.04 (0.95, 1.14)	1.0(ref)	1.15 (1.05, 1.25)
Yes	1032	2.21 (1.27, 3.83)	1.54 (0.85, 2.81)	1.08 (0.57, 2.06)	1.0(ref)	1.24 (0.65, 2.37)
ARDS
No	44198	1.99 (1.82, 2.17)	1.24 (1.14, 1.36)	1.04 (0.95, 1.14)	1.0(ref)	1.15 (1.05, 1.26)
Yes	788	1.33 (0.77, 2.32)	1.37 (0.79, 2.36)	1.08 (0.63, 1.88)	1.0(ref)	1.04 (0.61, 1.79)
RRT
No	42710	1.99 (1.82, 2.17)	1.21 (1.11, 1.33)	1.04 (0.95, 1.14)	1.0(ref)	1.13 (1.03, 1.24)
Yes	2276	1.69 (1.21, 2.37)	1.86 (1.32, 2.61)	1.17 (0.81, 1.70)	1.0(ref)	1.10 (0.80, 1.50)
PH
<7.35	9704	1.91 (1.65, 2.22)	1.21 (1.03, 1.42)	1.04 (0.88, 1.23)	1.0(ref)	1.29 (1.10, 1.50)
7.35-7.45	11850	1.67 (1.41, 1.98)	1.07 (0.90, 1.27)	1.11 (0.94, 1.30)	1.0(ref)	1.16 (0.99, 1.35)
≥7.45	5321	1.46 (1.15, 1.86)	0.91 (0.72, 1.15)	0.95 (0.77, 1.19)	1.0(ref)	0.90 (0.73, 1.11)
Albumin, g/dl
1 - 2.8	5927	1.02 (0.84, 1.24)	0.76 (0.62, 0.94)	0.91 (0.72, 1.15)	1.0(ref)	1.16 (0.90, 1.49)
2.9 - 3.4	5693	0.89 (0.71, 1.11)	0.84 (0.68, 1.05)	0.89 (0.72, 1.11)	1.0(ref)	1.29 (1.03, 1.61)
3.5 - 6.3	6881	1.35 (0.98, 1.87)	1.02 (0.76, 1.37)	0.91 (0.71, 1.17)	1.0(ref)	1.11 (0.92, 1.35)

AKI: acute kidney injury; CKD: chronic heart failure; ARDS: acute respiratory distress syndrome; RRT: renal replacement therapy.