Review Article

Targeting CD36 as Biomarker for Metastasis Prognostic: How Far from Translation into Clinical Practice?

Table 2

Clinical trials investigating CD36 expression.

NoConditionsTitleInterventionsIdentifier

1Healthy Young/ElderlyEffects of Native Whey or Milk Supplementation on Adaptations to 12 Weeks of Strength Training in Young and ElderlyDietary Supplement: Native whey|Dietary Supplement: Milk|Other: Strength trainingNCT03033953
Anabolic Effects of Whey and Casein After Strength Training in Young and ElderlyStrength training|Dietary Supplement: Milk 1%|Dietary Supplement: Whey protein concentrate 80|Dietary Supplement: Native wheyNCT02968888

2Taste Sensitivity|Fatty Acid TypeFatty Acid Taste Thresholds: Caproic, Lauric, Oleic, Linoleic, LinolenicNCT01996566

3Obesity/Metabolic SyndromeCD36 and Human Fat Taste PerceptionNo interventionNCT02699567
Metabolic and Cardiovascular Impact of CD36 Deficiency in African AmericansNCT02126735
Study 8: Fat Perception in Humans (09-0873)NCT01128400
Study 19: Metabolically Normal and Metabolically Abnormal ObesityBehavioral: overfeedingNCT01184170

4Insulin Resistance|Endothelial DysfunctionCD36 in Nutrient Delivery and Its DysfunctionSildenafil Citrate (Viagra)NCT03012386

5Type 2 Diabetes or Obesity Without DiabetesSearch for Biological Markers of Orosensory Perception of Fatty Acids in Healthy Subjects and Possible Modifications in Patients With Type 2 Diabetes and in Obese Non-diabetic Patients.Other: Measure the threshold of detection for linoleic acid|Other: Oral stimulation tests|Other: Venous blood samples|Other: Samples for genetic studies (ancillary study)NCT02028975

6Moderate Hypertriacylglycerolemic SubjectsIntervention With n3 LC-PUFA-supplemented YogurtDietary Supplement: n3 long chain polyunsaturated fatty acidsNCT01244048

7Diabetes Mellitus, Type 2|Dyslipidemia Associated With Type II Diabetes Mellitus|Percutaneous Coronary InterventionEffects of Evolocumab on Platelet Reactivity in Patients With Diabetes Mellitus After Elective Percutaneous Coronary InterventionDrug: Evolocumab|Drug: PlaceboNCT03258281

Insulin Resistance|Diabetes|Cancer|Obesity|InflammationStudy 14: Diet and Metabolic InflammationOther: Diet A|Other: Diet BNCT02539355

Renal Failure Chronic Requiring Hemodialysis|Metabolic Syndrome|Diabetes Mellitus Type 2|HyperlipidemiaStudy 16: Salusin-alpha - a New Factor in the Pathogenesis of Lipid Abnormalities in Hemodialysis PatientsDrug: AtorvastatinNCT01448174

Cardiovascular AbnormalitiesStudy 13: A Study of Immunological Biomarkers as Predictors of Cardiovascular EventsOther: blood testsNCT02894060

Coronary Artery DiseasePolymorphisms in CD36 and STAT3 Genes and Different Dietary Interventions Among Patients With Coronary Artery DiseaseDietary Supplement: Olive oil|Dietary Supplement: Nuts|Dietary Supplement: Control dietNCT02202265

ThrombocytopeniaStudy 5: Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH CampusNoneNCT00015639

Idiopathic Thrombocytopenic PurpuraThe Effect of Eltrombopag on the Expression of Platelet Collagen Receptor GPVI in Pediatric ITP.Drug: Eltrombopag|Drug: conventionalNCT03412188

Myelodysplastic SyndromesStudy 22: Azacitidine and Erythropoietin Versus Azacitidine Alone for Patients With Low-Risk Myelodysplastic SyndromesAzacitidine|Drug: Erythropoietin|Drug: Azacitidine (Monotherapy)NCT00379912

Rheumatoid ArthritisStudy 7: A New Mode of Action of Anti-TNF, Reverse Signaling, in Rheumatoid ArthritisDiagnostic Test: Blood testNCT03216928

Rheumatoid ArthritisAtherosclerosis in Rheumatoid Arthritis and Lupus: Restoring Cholesterol BalanceNCT01180361

SLE|Rheumatoid Arthritis|Healthy SubjectsStudy 15: Efferocytosis and Genomic Polymorphism in Autoimmune DiseasesNCT00364728

HIV InfectionsStudy 12: Maraviroc 300 mg Twice Daily in HIV Negative Male VolunteersDrug: MaravirocNCT00771823