Research Article
Identification of Genetic Risk Factors for Neonatal Hyperbilirubinemia in Fujian Province, Southeastern China: A Case-Control Study
Table 4
Comparison of frequencies of the alleles in each SNP locus of the UGT1A1, OAP1B1, and HO-1 genes between the case and control groups.
| | Gene | SNP locus | Allele | Frequency in the case group() | Frequency in the control group () | χ2 | P | OR(95%CI) |
| | UGT1A1 | (TA)n repeat rs8175347 | TA6 | 92.1 | 90 | 1.503 | 0.22 | 1 | | TA7 | 7.9 | 10 | 1.301 (0.853–1.984) | | rs4148323 | G | 70.1 | 81 | 16.98 | 0 | 1 | | A | 29.9 | 19 | 1.818 (1.365–2.421) | | OAP1B1 | rs2306283 | G | 75.2 | 75.2 | 0 | 0.992 | 1 | | A | 24.8 | 24.8 | 1.001 (0.758–1.322) | | HO-1 | (GT)n repeat rs1805173 | L | 44.2 | 54 | 6.114 | 0.013 | 1 | | M | 22.2 | 21.6 | 1.255 (0.922–1.709) | | S | 33.6 | 24.4 | 1.680 (1.264–2.232) |
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