2³ Full Factorial Model for Particle Size Optimization of Methotrexate Loaded Chitosan Nanocarriers: A Design of Experiments (DoE) Approach

Table 3

Descriptive statistics of fitted linear model.

Statistical term	Value
Model p value	<0.0001
Chitosan p value	<0.0001
TPP p value	0.003
MTX p Value	<0.0001
Regression coefficient (R^2)	0.9958
Predicted Regression coefficient ()	0.9912
Adjusted Regression coefficient ()	0.9940
Coefficient of variance (%CV)	1.50%
Adequate Precision	65.94