BioMed Research International / 2018 / Article / Tab 3

Review Article

A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less?

Table 3

Association between hyperoxemia and clinically relevant outcomes in sepsis.

Reference Study designSample sizeHyperoxemia definitionConditionLocationConclusion

[19], Stolmeijer et al.Prospective cohort83PaO2 > 13.5 kPaSepsisEDMore than 64% of patients were hyperoxemic with 10 L O2/min. No association with mortality.

[47], Rossi et al.Prospective cohort14FiO2 100%SepsisICUDecreases oxygen delivery in upper limbs.

[48], Pope et al.Retrospective cohort619Central venous saturation (ScvO2) 90–100%SepsisEDAssociated with increased mortality.

[49], Dahl et al.Retrospective cohort1,770PaO2 16.0 kPaSepsisICUNo effect on mortality, but hypoxemia and FiO2 60% increased mortality.

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