Two Transcripts of FBXO5 Promote Migration and Osteogenic Differentiation of Human Periodontal Ligament Mesenchymal Stem Cells

<div>Knockdown of FBXO5 attenuated the migration of hPDLSCs. (a, b, c, d) hPDLSCs were infected with FBOX5 shRNA. Western blot (a) and quantitative analysis (b) results revealed the decreased expression of FBXO5 after the depletion of FBXO5. Real-time RT-PCR results showed the decrease in the expression of transcript a (c) and transcript b (d) after FBXO5 depletion. Scratch migration assay (e) and quantitative analysis (f) results revealed that FBXO5sh group showed a significant decrease in the rate of wound closure as compared with CONTsh group. GAPDH was used as an internal control. 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BioMed Research International

fig2

Figure 2

Figure 2: Two Transcripts of FBXO5 Promote Migration and Osteogenic Differentiation of Human Periodontal Ligament Mesenchymal Stem Cells 