Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma

Figure 1

Growth characteristics of xenotransplants and cell cultures. (a) Growth rate of xenotransplants (10 samples); tumor tissue was harvested with a diameter of around 1 cm from week 10 on (highlighted in orange); (b) tumor growth visible from outside in NMRI mouse 73 days after xenotransplantation at 2 sites dorsally (orange arrows); (c) after euthanasia with macroscopically visible tumors located subcutaneously (orange arrows); scale bars: 1 cm. (d) Cell culture 56 days after dissociation (5x magnification); (e) spheroid colonies 6 days after transfer to ultralow attachment conditions (5x magnification).