Research Article
Elevated TERT Expression in TERT-Wildtype Adult Diffuse Gliomas: Histological Evaluation with a Novel TERT-Specific Antibody
Table 1
Molecular information of the cases.
| Classification | Number | TERT mt | TERT SNP | IDH1/2 mt | p53 IHC | ATRX IHC | 1p/19q-codel | C228T (%) | C250T (%) | T349C (%) | (%) | (%) | (%) | (%) |
| Astrocytic with IDH-mutant (DA/AA) | 11 | 0 | 0 | 54.5 | 100 | 72.7 | 0 | 0 | Oligodendroglial | 10 | 70 | 30 | 30 | 100 | 0 | 100 | 100 | GBM | 11 | 45.5 | 18.2 | 90.9 | 0 | 27.3 | 100 | 0 | DA/AA with IDH-wildtype | 9 | 33.3 | 11.1 | 33.3 | 0 | 0 | 100 | 0 |
| Total | 41 | 36.6 | 14.6 | 53.7 | 51.2 | 26.8 | 73.2 | 24.4 |
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AA, anaplastic astrocytoma; codel, codeletion; DA, diffuse astrocytoma; GBM, IDH-wildtype glioblastoma; IHC, immunohistochemistry; mt, mutation.
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