Elevated TERT Expression in TERT-Wildtype Adult Diffuse Gliomas: Histological Evaluation with a Novel TERT-Specific Antibody

Table 1

Molecular information of the cases.

Classification	Number	TERT mt		TERT SNP	IDH1/2 mt	p53 IHC	ATRX IHC	1p/19q-codel
		C228T (%)	C250T (%)	T349C (%)	(%)	(%)	(%)	(%)
Astrocytic with IDH-mutant (DA/AA)	11	0	0	54.5	100	72.7	0	0
Oligodendroglial	10	70	30	30	100	0	100	100
GBM	11	45.5	18.2	90.9	0	27.3	100	0
DA/AA with IDH-wildtype	9	33.3	11.1	33.3	0	0	100	0
Total	41	36.6	14.6	53.7	51.2	26.8	73.2	24.4

AA, anaplastic astrocytoma; codel, codeletion; DA, diffuse astrocytoma; GBM, IDH-wildtype glioblastoma; IHC, immunohistochemistry; mt, mutation.