Polymorphisms in Autophagy-Related Gene IRGM Are Associated with Susceptibility to Autoimmune Thyroid Diseases

Table 2

Allele and genotype frequencies of IRGM SNPs in controls and AITD patients.

SNP	Genotype/Allele	Control (%)	AITD (%)		OR	95% CI
rs10065172	CC	275 (34.854)	238 (30.51)
	CT	380 (48.162)	398 (51.03)	0.183	-	-
	TT	134 (16.984)	144 (18.46)
	C	930 (58.94)	874 (56.03)	0.099	1.126	0.978-1.298
	T	648 (41.06)	686 (43.97)
rs4958847	AA	293 (37.14)	325 (41.67)
	AG	380 (48.16)	355 (45.51)	0.162	-	-
	GG	116 (14.70)	100 (12.82)
	A	966 (61.22)	1005 (64.42)	0.063	0.872	0.754-1.008
	G	612 (38.78)	555 (35.58)
rs13361189	TT	275 (34.85)	239 (30.64)
	CT	379 (48.04)	398 (51.03)	0.205	-	-
	CC	135 (17.11)	143 (18.33)
	T	929 (58.87)	876 (56.15)
	C	649 (41.13)	684 (43.85)	0.124	1.118	0.970-1.288

AITD, autoimmune thyroid disease; OR, odds ratio; 95% CI, 95% confidence intervals.