Research Article
Polymorphisms in Autophagy-Related Gene IRGM Are Associated with Susceptibility to Autoimmune Thyroid Diseases
Table 5
Haplotype analysis of case groups and healthy control group.
| | Haplotype | Controls (%) | AITD | P | OR (95%CI) | GD (%) | P | OR (95%CI) | HT (%) | P | OR (95% CI) |
| | CTA | 645
(40.98) | 679
(43.64) | 0.132 | 1.115 (0.968-1.285) | 441 (45.28) | 0.030 | 1.195
(1.017-1.404) | 238 (40.89) | 0.975 | 0.997 (0.822-1.210) | | TCG | 610
(38.75) | 548
(35.22) | 0.044 | 0.861 (0.745-0.996) | 331 (33.98) | 0.017 | 0.816
(0.690-0.964) | 218 (37.46) | 0.568 | 0.944 (0.776-1.149) | | TCA | 318
(20.20) | 321
(20.63) | 0.734 | 1.031 (0.866-1.226) | 197 (20.23) | 0.989 | 1.001
(0.821-1.222) | 124 (21.31) | 0.560 | 1.072 (0.849-1.354) |
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AITD, autoimmune thyroid disease; GD, Graves’ disease; HT, Hashimoto’s thyroiditis; OR, odds ratio; 95% CI, 95% confidence intervals.
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