BioMed Research International / 2018 / Article / Tab 1

Research Article

Blood Lactate or Lactate Clearance: Which Is Robust to Predict the Neurological Outcomes after Cardiac Arrest? A Systematic Review and Meta-Analysis

Table 1

Characteristics of included clinical studies.

StudiesYearDesignCountryAge (mean)Sex, M/FLocation of CAPercentage of initial shockable rhythmNo.Outcome follow upHypothermia (%)Measure fromNeurological outcomes
(G/P)
Lactate level on admission (G/P) (mmol/L)

Mullner [12]1997RetrospectiveAustralia62152/15OHCAVF (100%)1676 mNoneArterial73/94-
Kliegel [13]2004RetrospectiveAustralia58282/112IHCA/OHCAVF/VT (65.5%)3946 mNoneArterial186/2087.77/9.33
Adrie [14]2006ProspectiveFrance5795/35OHCAVT/VF (42%)130DC11None28/1023.27/8.43
Shinozaki [15]2011ProspectiveJapan6863/35OHCAVF/VT (14.3%)986 m20None10/887.61/11.84
Cho [16]2012RetrospectiveKorea51.382/25OHCAVF/VT (29.9%)1171 m100None34/838.89/9.53
Lee [3]2013RetrospectiveKorea51.748/28OHCAVF (43.4%)761 m100Venous34/426.07/7.13
Maekawa [17]2013ProspectiveJapan5444/8OHCAVF/VT (59.6%)523 m50Arterial8/4412.70/16.97
Donnino [4]2014ProspectiveUSA6360/40OHCAVF/VT (55%)100DC97None30/164.23/6.80
Jensen [18]2014ProspectiveNorway59.287/24OHCAVF/VT (79.3%)111DC100None53/586.50/9.60
Kaji [19]2014RetrospectiveUSA6598/86OHCAVT/VF (35.9%)184DC63.2None43/1413.47/6.57
Matsumoto [10]2014ProspectiveJapan49.111/2OHCAVF (100%)131 m100Arterial7/612.25/13.15
Mochizuki [20]2014RetrospectiveJapan5133/17OHCAVF/VT (54%)501 m32None10/4010.94/14.73
Oksanen [21]2014RetrospectiveFinland58.689/20OHCAVF (100%)109DC100None81/283.00/3.63
Lee [22]2015RetrospectiveKorea57.7295/148OHCAVF (22.6%)443DC100None96/3478.99/10.70
Nagata [23]2015RetrospectiveJapan76.839/16OHCAVT/VF (45.5%)55DC45.5None21/343.23/5.11
Ryu [24]2015RetrospectiveKorea5880/35IHCA/OHCAVT/VF (42%)115DC8.0None68/477.87/12.27
Ono [25]2016ProspectiveJapan70.5180/135OHCAVT/VF (24.1%)3151 m30.2None51/2645.37/9.27
Yannopoulos [26]2016ProspectiveUSA18-7514/4OHCAVF (100%)181 m100None9/99.90/14.60
Dell'Anna [27]2017RetrospectiveBelgium63155/81IHCA/OHCAVT/VF (42%)2363 m100Arterial74/1623.17/5.73
Kim [28]2017RetrospectiveKorea60.5183/99IHCA/OHCAVT/VF (35.5%)282DC100Arterial98/1846.46/7.6
Momiyama [29]2017RetrospectiveJapan73236/136OHCAVT/VF (89%)372DC100Arterial31/3415.26/6.15
Orban [30]2017RetrospectiveFrance65192/80OHCAVT/VF (44%)272DC100Arterial89/1832.43/6.03
Shinozaki [31]2017ProspectiveUSA70.81772/973OHCAVT/VF (42%)30113 mNoneNone380/23657.03/11.70

CA: cardiac arrest; DC: discharge from hospital; G: good neurological outcomes; IHCA: in hospital CA; N: no information; m: month; OHCA: out of hospital CA; P: poor neurological outcomes; VF: ventricular fibrillation; VT: ventricular tachycardia.

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