Combination Use of BMP2 and VEGF165 Promotes Osseointegration and Stability of Titanium Implants in Irradiated Bone

Figure 4

(a) 3D reconstructed images of implant and contacting bone tissues based on Micro-CT images. White color represents implants and yellow color represents bone tissues. (A) Control at 2 weeks; (B) HBO at 2 weeks; (C) BMP2 at 2 weeks; (D) VEGF165 at 2 weeks; (E) BMP2/VEGF165 at 2 weeks; (F) control at 8 weeks; (G) HBO at 8 weeks; (H) BMP2 at 8 weeks; (I) VEGF165 at 8 weeks; (J) BMP2/VEGF165 at 8 weeks; (b) BV/TV; (c) Tb.Th; (d) Tb.N; (e) Tb.Sp. P < 0.05. All values are expressed as mean ± SD, N=5.

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