Research Article

Assessment of Extrapulmonary Tuberculosis Using Gene Xpert MTB/RIF Assay and Fluorescent Microscopy and Its Risk Factors at Dessie Referral Hospital, Northeast Ethiopia

Table 4

Factors associated with Gene Xpert MTB/RIF assay positivity among presumptive EPTB cases at Dessie Referral Hospital, from March 1 to June 30, 2017.

Variable Freq Xpert result COR (95%CI)P-valueAOR (95%CI)p-value
Negative=n (%)Positive=n (%)

Age in years
 18-30132119(90.2)13(9.8)ref
 31-50161147(91.3)14(8.7)0.87(0.40-1.93)0.734
 >506056(93.3)4 (6.7)0.65(0.20-2.10)0.475

Sex
 Male185170(91.9)15(8.1)ref
 Female168152(90.5)16(9.5)1.19(0.57-2.49)0.639

Residence
 Urban171161(94.2)10(5.8)ref
 Rural182161(88.5)21(11.5)2.1(0.95-4.60)0.0642.14(0.97-4.71)0.059

Marital status
 Married262238(90.8)24(9.2)ref
 Single9184(92.3)7(7.7)0.83(0.34-1.99)0.670

Occupation
 House wife9988(88.9)11(11.1)ref
 Merchant8479(94.0)5(6.0)0.51(0.17-1.52)0.225
 Farmer9383(89.2)10(10.8)0.96(0.39-2.39)0.937
 Others7772(93.5)5(6.5)0.56(0.19-1.67)0.296

Educational Status
 Illiterate143128(89.5)15(10.5)1.84(0.73-4.68)0.199
 Grades 1-89384(90.3)9(9.7)1.68(0.60-4.71)0.320
 Grade 9 & above117110(94.0)7(6.0)ref

Monthly income
 <1500 birr213191(89.7)22(10.3)1.68(0.75-3.76)0.209
 >1500 birr140131(93.6)9(6.4)ref

Family size
 <4137125(91.2)12(8.8)ref
 4 & above216197(91.2)19(8.8)1.0(0.47-2.14)0.990

Cigarette Smoking
 Yes2722(81.5)5(18.5)2.6(0.92-7.50)0.072
 No326300(92.0)26(8.0)ref

Alcohol drinking
 Yes5245(86.5)7(13.5)1.8(0.73-4.41)0.20
 No301277(92.0)24(8.0ref

Previous PTB
 Yes3226(81.2)6(18.8)2.73(1.03-7.26)0.0442.8(1.05-7.54)0.040
 No321296(92.2)25(7.8)ref

Chronic disease
 Yes173156(90.2)17(9.8)1.29(0.62-2.71)0.497
 No180166(92.2)14(7.8)ref

Contact with PTB patients
 Yes1612(75.0)4(25.0)3.83(1.16-12.68)0.028
 No337310(92.0)27(8.0ref

Consumption of raw milk
 Yes5248(92.3)4(7.7)0.86(0.28-2.53)0.764
 No301274(91.0)27(9.0)ref

COR: crude odds ratio; AOD: adjusted odds ratio.