Effect of Hypoxia-Inducible Factor 1α on Early Healing in Extraction Sockets
Table 3
Histomorphometric data of the three regions of interest (ROIs) within the socket.
Control
HIF1A
value
NB (mm2)
Coronal1/3
0.46 ± 0.50
0.67 ± 0.39
0.463
Middle1/3
0.65 ± 0.49
1.01 ± 0.19
0.204
Apical1/3
1.01 ± 0.42
1.08 ± 0.27
0.767
RM (mm2)
Coronal1/3
0.66 ± 0.42
0.26 ± 0.31
0.141
Middle1/3
0.33 ± 0.30
0.07 ± 0.11
0.080
Apical1/3
0.00 ± 0.01
0.06 ± 0.14
0.655
BV ()
Coronal1/3
26.17 ± 11.70
30.33 ± 10.11
0.320
Middle1/3
28.67 ± 8.31
36.50 ± 10.09
0.108
Apical1/3
29.00 ± 13.91
31.50 ± 16.17
0.207
Data are expressed as mean ± SD. The dimension of each ROI was 2.0 mm2. NB, the area of newly formed bone; RM, the area of residual bone substitute material; BV, the number of blood vessels.
