Antidepressant Effect of Fraxinus rhynchophylla Hance Extract in a Mouse Model of Chronic Stress-Induced Depression

Figure 3

Effect of FX extract on the expression of NF-B, TNF-, IL-6, and IL-12 mRNA. (a) The expression of NF-κB p65 mRNA in the prefrontal cortex and hippocampus in all groups (n = 4). (b-d) The expression of the inflammatory cytokines, IL-12, IL-6, and TNFα mRNA in the prefrontal cortex and hippocampus (n = 3-4). Mean ± SD. P < 0.05, P < 0.01, and P < 0.001 versus normal group; P < 0.05, P < 0.01, and P < 0.001 versus control group.

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