Growth Media Affect Assessment of Antimicrobial Activity of Plant-Derived Polyphenols

Table 1

Effects of EGCG and the other test agents on the growth of selected oral bacteria.

Strains	MIC (µg/mL)
	EGCG		Grape seed extract		Berberine chloride		Methyl salicylate		Chlorhexidine gluconate
	CDM	BHI	CDM	BHI	CDM	BHI	CDM	BHI	CDM	BHI
S. mutans	78.1	625	125	>500	125	125	>3%	>3%	2.5	5
ATCC 25175
S. mutans	39.1	625	125	>500	125	125	>3%	>3%	2.5	5
UA159
S. mutans	78.1	625	62.5	>500	125	250	3%	>3%	5	5
Ingbritt
S. gordonii	≤9.8	625	>500	>500	125	250	0.75%	>3%	10	10
ATCC 49818
S. sanguinis	≤9.8	312.5	>500	>500	125	250	>3%	>3%	10	10
ATCC 10556
S. sobrinus	19.5	1250	62.5	>500	62.5	125	3%	>3%	5	5
ATCC 6715
A. actinomycetemcomitans	39.1	156.3	250	>500	125	250	0.75%	0.75%	5	10
ATCC 43718
E. faecalis	39.1	>1250	62.5	>500	500	>500	>3%	>3%	20	20
ATCC 29212

The unit of MIC values is % of methyl salicylate (vol/vol).