Uroplakin IIIa Is a Marker in Bladder Cancer but Seems Not to Reflect Chemical Carcinogenesis

Table 2

UPIIIa level in plasma and urine in BC and control group C.

Group	UPIIIa in urine [ng/mg cr.]			UPIIIa in plasma [ng/ml]			p-value
	Mean	SD	Me	Mean	SD	Me	in urine	in plasma
C	1.02	0.54	0.98	0.58	0.31	0.65	p≤0.001	p≤0.001
BC	2.44	1.41	2.11	1.47	0.76	1.32	BC vs C	BC vs C
NMIBC	2.38	1.36	2.10	1.37	0.56	1.25	p=0.5978	p=0.4312
MIBC	2.64	1.59	2.23	1.77	1.15	1.32	NMIBC vs MIBC	NMIBC vs MIBC
LG	2.44	1.37	2.11	1.42	0.62	1.32	p≤0.001	p≤0.001
							LG vs C	LG vs C
HG							p=0≤0.001	p≤0.001
	2.44	1.48	2.21	1.52	0.90	1.22	HG vs C	HG vs C
							p=0.9945	p=0.9939
							LG vs HG	LG vs HG
Non-smoking BC	2.02	1.11	2.02	0.96	0.61	0.96	p> 0.05	p> 0.05
Smoking BC	2.11	1.48	2.11	1.32	0.81	1.32	non-smoking BC	non-smoking BC
							vs smoking BC	vs smoking BC
Non-smoking C	1.28	0.41	1.17	0.68	0.33	0.69	p>0.05	p>0.05
Smoking C	0.94	0.56	0.91	0.553	0.30	0.65	non-smoking C	non-smoking C
							vs smoking C	vs smoking C

UPIIIa: uroplakin IIIa; C: control group; BC: patient group; NMIBC: nonmuscle invasive BC; MIBC: muscle invasive BC; LG: low grade; HG: high grade; SD: standard deviation; p: statistically significant difference; Me: median